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Cell Architecture
Open Postdoctoral Positions

Connecting the nucleus to the cytoskeleton is relevant for multiple cellular processes and disruption of these connections result in multiple pathologies. Nuclear positioning within cell cytoplasm requires de connection between nucleus and the cytoskeleton.

We are interesting to understand the processes involved in these connections and the role for nuclear positioning in cell function.

We study cell migration and skeletal myofiber formation which required the connection between the nucleus and the cytoskeleton and precise nuclear positioning. We use different molecular and cellular approaches in combination with time-lapse imaging analysis to address these questions.


Research Team

Ana Sofia Carvalho Marques
MSc Student

Cátia Janota
PhD Student

David Barata
Post-Doctoral Researcher

Francisco Calero
Post-Doctoral Researcher

Graciano Leal
Post-Doctoral Researcher

Helena Pinheiro
PhD Student

Inês Martins
Lab Technician

João Martins
PhD Student

Judite Costa
Lab Manager

Katharina Hennig
Post-Doctoral Researcher

Lilian Sluimer
MSc Student

Luis Oliveira
Lab Technician

Sara Ferreira
Lab Technician

William Roman
Post-Doctoral Researcher

Research Areas

  • Mechanisms of nuclear movement during cell migration and skeletal muscle formation
  • Role for nuclear positioning in skeletal muscle formation

Ongoing Research Projects

2019-2025: ERC Synergy

2018-2022: FETOPEN - MyoChip Project

2018-2021: FCT LISBOA-01-0145-FEDER-031075

2018-2020: AFM-Telethon

2014-2019: EMBO Installation Grant


Previous Research Projects

2016-2018: ERC proof of concept Grant

2016-2019: Coordinator of H2020-TWINN-2015 Cancer Biology consortium

2014-2019: ERC Consolidator Grant

2014-2019: EMBO Installation Grant

2014-2019: Investigador FCT

Selected Publications

group leader :
Edgar R. Gomes