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Master Training

iMM regularly hosts students to conduct their Master Thesis Projects within several of our Research Groups.

List of Master Projects for 2020/2021

Cellular and molecular regulators of the anti-tumor γδ T cell response in the tumor microenvironment

Supervisors: Karine Serre and Noella Lopes Pappalardo
Lab: Bruno Silva-Santos Lab
Contact: and

Antibiofilm effect of a fish-derived antimicrobial peptide on Gram-positive and Gram-negative bacteria

Supervisors: Sónia Gonçalves and Nuno C. Santos
Lab: Nuno Santos Lab
Contact: and

miRNA:mRNA regulatory networks in the differentiation of pro-inflammatory γδ T cell subsets

Supervisors: Bruno Silva-Santos and Anita Q. Gomes
Lab: Bruno Silva-Santos Lab
Contact: and

Revealing lung repair through IL-22 pathway

Supervisor: Susana M. Fernandes
Lab: Ana Espada Sousa Lab

Unveiling the role of SAMHD1 in the differentiation of follicular helper T cells and its relation to HIV susceptibility

Supervisors: Ana Catarina Godinho Santos and Ana Espada de Sousa
Lab: Ana Espada Sousa Lab
Contact: and

Shaping monocyte / macrophage system to control HIV/AIDS pathogenesis: lessons from HIV-2

Supervisors: Amelia Chiara Trombetta and Afonso Almeida
Lab: Ana Espada Sousa Lab
Contact: and

Development of combined gene expression and alternative splicing signatures for the ageing of human tissues

Supervisors: Nuno Barbosa Morais
Lab: Nuno Morais Lab

Deciphering the molecular paths towards cancer development and cell differentiation

Supervisor: Sérgio de Almeida
Lab: Sérgio de Almeida Lab

Investigating the role of LINE-1 elements in X-chromosome inactivation and gene expression through functional approaches

Supervisor: Anne-Valerie Gendrel
Lab: Sérgio de Almeida Lab

Understanding the roles of the long noncoding RNA TERRA in telomerase-independent telomere elongation in ALT cancer cells

Supervisor: Claus M. Azzalin
Lab: Claus M. Azzalin Lab

Deciphering the protein fingerprint of brain mitochondria

Supervisor: Vanessa A. Morais
Lab: Vanessa Morais Lab

Gut Permeability in Children and Adults with Systemic Lupus Erythematosus

Supervisors: Patrícia Costa Reis and Ângelo Calado
Lab: João Eurico Fonseca Lab
Contact: and

Sequence determinants of transcriptional pausing

Supervisors: Rosina Savisaar
Lab: Maria Carmo-Fonseca Lab

Mechanisms of nuclear positioning during metastasis

Supervisor: Edgar Gomes
Lab: Edgar Gomes Lab

Mechanisms of nuclear positioning in skeletal muscle cells

Supervisor: Edgar Gomes
Lab: Edgar Gomes Lab

In vitro characterization of a PbWsp transmission-blocking vaccine candidate

Supervisors: Miguel Prudêncio, Raquel Azevedo, and António M. Mendes
Lab: Miguel Prudêncio Lab
Contact:,, and

Identify Plasmodium immunomodulatory molecules proteins that contribute to the success/failure of vaccination

Supervisors: António M. Mendes, Helena Nunes Cabaço and Miguel Prudêncio
Lab: Miguel Prudêncio Lab
Contact:, and

CITO-CERENE – CIrculating TumOr Cell Reducing NEphrectomy

Supervisor: Tito Palmela Leitão
Lab: Luís Costa Lab

Application to Master Projects

1. Application Process

  1. Candidates should choose their preferred Project from the list indicated above.
  2. Candidates should email potential iMM Master Project supervisors providing the following documents:
  • CV: including candidate´s contact info; info on completed/ongoing degrees and respective Graduate School and University (Faculdade/Universidade); quantitative info on academic performance up to date e.g. final average grade (or discriminated grades, if applicable); info on prior research training (if applicable); English fluency; etc.
  • Motivation Letter: statement explaining how the candidate´s prior academic path and future professional plans fit within the scope of the specific Master Project.
  • References: contact info (email and phone) of two References. References may be Professors who know the candidate well as a student, or Supervisors of prior research training, etc
  • Please note that Supervisors email contacts are provided in the List indicated above.

2. Selection

Selection is made directly by each potential iMM Supervisor.

Supervisors may decide based on application documents only or eventually get in touch directly with the References, or invite the candidates for interview.

Each Master training position is open until filled. Candidates are informed of the selection process outcome directly by potential Supervisors.

Master Course in Biomedical Research

Application Period: May 25th - July 10th, 2020

Starting Date: October 2020

To apply please visit:
More info on how to apply:


We offer a multidisciplinary, transversal and integrated Master training from the bench to the bedside grounded on the four major areas of biomedical research: (i) cell biology and cancer; (ii) neurosciences; (iii) cardiovascular biology, (iv) infection and immunity.

Our methodology stimulates self-learning through teaching in small work groups, with systematic assessment of knowledge, skills and attitudes.

The students will have the opportunity to pursue their research projects within the Lisbon Academic Medical Centre environment with top scientists and a vibrant atmosphere, obtaining state-of-the-art biomedical training in our unique setting combining the Hospital, Medical School and Research Institutes, where teams of researchers are working together.


Prepare independent, critical, creative, curious, and pioneer researchers with a strong training on the application of the scientific method to pursue a doctoral degree in Biomedicine.

The strategy is based on tutorial and selective teaching in advanced technologies and methodologies and their relevance and application to a set of biomedical problems.

Skills Acquisition

Students will be stimulated to advance learning of critical skills required to enroll in a doctoral program.

Technical skills: training through research, imaging, analytical techniques, cell and molecular biology, computational biology, use of animal models, data analysis.

Transversal skills: scientific drafting, communication, bioethics, management, critical thinking, autonomy, creativity.

Career Prospects

Biomedical research in academia or industry, doctoral degree in Biomedicine.

Admission Requirements & Selection Criteria

A first cycle degree or above in any scientific area.

We welcome applications from highly qualified and motivated students of all nationalities.

Two-step evaluation process:
Step 1 - Assessment of the CV of applicant and personal statement.
Step 2 - Interview (Only selected applicants from Step 1 will be considered for Step 2).

Language & Vacancies

The course will be held in English.
Maximum 10 students will be accepted for this Master Course.

Application & Tuition Fees

The application has a 100€ fee.
All tuition fees will be fully supported by Instituto de Medicina Molecular João Lobo Antunes (iMM) scholarship.

Study Plan

Scientific Commitee

Luís Graça, MD, PhD (Coordinator)
Pedro Simas, PhD
Cláudio Franco, PhD
Luísa V. Lopes, PhD
Edgar Gomes, PhD


Training Hub iMM: