Leverage research EXCELLence and INNOVation potential of Instituto de Medicina Molecular João Lobo Antunes (iMM) through translational biomedical research in immunity and infection.
Funding Agency: European Commission
Funding Programme: Horizon 2020
Call/Topic: H2020-WIDESPREAD-2014-2 / WIDESPREAD-2-2014 - ERA Chairs
Project Reference: 667824
Start Date: 2015.01.07
Duration: 60 months
Total Investment: EUR 2,777,183.15 (EU contribution EUR 2,499,465)
Project Coordinator: Maria Mota
This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 667824.
EXCELLtoINNOV will provide iMM with the needed means to achieve excellence on a sustainable basis through the recruitment of an ERA Chair in pre-clinical molecular and imaging studies, in immunity and infection.
This goal will be strategically achieved by placing iMM in the forefront of Research, Development and Innovation (R&D+I) in immunity and infection, through the establishment of a translational biomedical research hub anchored in Lisbon that will:
- Leverage the national potential beyond borders;
- Act as the interface of Europe with America and Africa;
- Effectively contribute to overcome the health and demographic change societal challenges by potentiating major scientific advancements in this research area through worldwide collaborative efforts.
The successful implementation of this strategy will be possible through specific activities, including:
- The development of a new research field at iMM by the ERA Chair holder, pre-clinical molecular and imaging studies, that will transversally benefit and impact all research areas at iMM;
- The implementation of structural changes at iMM to successfully support and comply with ERA priorities;
- The expansion of overseas collaborations in international collaborative R&D+I projects;
- An improved integration of iMM in the regional, national and international business community.
Through the completion of these activities we will achieve an improved capability to compete successfully for internationally competitive research funding, including but not limited to Horizon 2020, IMI2 and EDCTP2 as well as effectively contribute to the objectives of regional smart specialisation strategies through increased international attractiveness, competitiveness and innovation potential of iMM, Lisbon and Portugal.
EXCELLtoINNOV project has one key central Work Package, ERA Chair recruitment, supported and complemented by other five additional Work Packages, designed to achieve concrete objectives.
WP1: Project management
Ensure the proper management of EXCELLtoINNOV, in order to achieve the objectives, milestones and deliverables of the project in due time. The basis for all types of management activities, from administrative to financial, is detailed. The management team will also set-up an effective communication infrastructure with regional, national and international partners of EXCELLtoINNOV network, as well as with the EC.
WP2: ERA Chair recruitment
Recruit the ERA Chair holder as well as his/her scientific team. The successful achievement of this objective will be potentiated through a worldwide dissemination of ERA Chair recruitment call.
WP3: Capacity building
Capacitate iMM in order to allow: raising the success rate of iMM in Horizon 2020 and diversify its participation in other EU co-funded initiatives; to boost iMM research excellence; and to potentiate a better integration of iMM in the business community.
WP4: Implementation of ERA priorities
Contribute to the implementation of ERA priorities through the implementation of The European Charter for Researchers & The Code of Conduct for the Recruitment of Researchers, by following the Human Resources Strategy for Researchers (HRS4R) and attainment and maintenance of the HR Excellence in Research logo.
WP5: International overseas cooperation
Establish a translational biomedical research hub anchored in Lisbon that will leverage the national potential beyond borders and act as the interface of Europe with America and Africa, through the establishment of a forum for overseas discussion in immunity and infection, the generation of a Database gathering experts in immunity and infection and the organisation of Expert visits to/from selected organisations in America and Africa.
WP6: International overseas cooperation
Ensure the proper dissemination and exploitation of the achievements of EXCELLtoINNOV project in the most efficient way. This will be achieved by: raising public and scientific awareness of the project and facilitating the interaction with scientific and non-scientific audiences, including the business community.
ERA Chair Holder and Team
Marc Veldhoen: ERA Chair Holder
- PhD (2003) at Open University, National Institute for Medical Research, London, UK
- Post-doctoral (2003-2006) research at Division of Molecular Immunology, National Institute for Medical Research, London, UK
- Senior Investigator Scientist (2006-2010) at Division of Molecular Immunology, National Institute for Medical Research, London, UK
- Group Leader (2010-2016), Laboratory of Lymphocyte Signalling and Development, at The Babraham Institute, Cambridge, UK
- Group Leader at iMM since 2016
Major Interests / Objectives:
Understanding Immune homeostasis and immunity in the small and large intestine. This includes the differences between the small and large intestine with respect to inflammatory responses. The difference between the intraepithelial lymphocytes (IEL) and lamina propria (LP) layers, e.g. the predominant type 1 response in the IEL compartment compared with an enriched IL-17 response in the LP compartment, the maintenance and generation of intra-epithelial lymphocytes (Innate and tissue resident T cells) and the interaction between epithelial cells and lymphocytes.
Furthermore we are interested in the balance between Type 1, 2 and 3 immune responses and how this relates to aberrant immunity such as autoimmunity, allergy as well as cancer.
Tiago Reis: Technical and Financial Project Manager.
Marta Baptista: Research assistant. Mouse genotyping, specialist in histology.
Cristina Ferreira: Senior post-doc. Expert in mouse experimentation and Flow cytometry.
Spela Konjar: Post-Doc.
Birte Blankenhaus: Post-Doc.
EXCELLtoINNOV – 1st Newsletter
The first Newsletter is out! Read it here.
EXCELLtoINNOV – 1st Annual Project Meeting
June 20-23, 2016
The first Annual Project Meeting of EXCELLtoINNOV was held at iMM, from 20-23rd of June, 2016. This was an excellent occasion for the analysis and discussion of the project progress by the Advisory Board, here represented by Maria M. Mota (project coordinator), Marc Veldhoen (ERA Chair), and two external members, namely Professor Herman Waldmann and Professor Artur Scherf. In addition, highly successful Capacity BuildingWorkshop – Leadership Course targeting the iMM postdoctoral community was integrated in this event as well as the publicly open seminar by the ERA Chair.
EXCELLtoINNOV Kick-off meeting: "How to Excell to Innov @ Lisbon Medical Centre"
October 12, 2015
The kick-off meeting of EXCELLtoINNOV was held at iMM, on October 12 2015. This meeting provided the opportunity to disseminate the project to the community as well as to promote an interactive debate with internal and external stakeholders. A panel of distinguished personalities was invited, including: the (at the time) Secretary of State for Science and Technology, Prof. Leonor Parreira; the Rector of the University of Lisbon, Prof. Cruz Serra; the Director of the Lisbon Medical School, Prof. Fausto Pinto; and Prof. Carmo-Fonseca and Prof. Maria Mota, President and Executive Director of iMM, respectively.
Chair in Immunity and Infection for outstanding researchers
July 1, 2015
The prestigious Horizon 2020 ERA Chair project, EXCELLtoINNOV, funded by the European Commission, takes off today, July 1st, with the launch of the recruitment process for the ERA Chair position.
January 4, 2017
You can view the informative brochure here
iMM organises the launching event of EXCELLtoINNOV
October 12, 2015 (available in PT only)
ERA Chair project (2.5 M€) funded by the European Commission's Horizon 2020 programme is launched
Four Portuguese institutions will receive approximately 10 million euros
February 14, 2014 (available in PT only)
Join the experts in immunity and infection research field to create a bigger interest among stakeholders, in order to develop more interaction among them, IMM and the scientific community.
This group offers engagement activities to the scientific community through the dissemination of new scientific data and by providing a Forum for overseas discussion in translational immunity and infection.
Please feel free to share and discuss articles published in peer reviewed journals, presentations in relevant international conferences and workshops, results, doubts, among other interactions.
Go to our Google Drive Folder where you can find news, seminars, job opportunities, funding opportunities, entrepreneurial opportunities, regulatory news, collaboration cases, a database of experts and papers.
What is EXCELLtoINNOV?
The project was envisioned to place iMM in the forefront of R&D+I in immunity and infection, through the recruitment of an ERA Chair and establishment of a translational biomedical research hub anchored in Lisbon. The successful implementation of this strategy includes:
- the development of a new research line at iMM by the ERA Chair holder which will transversally impact other research areas at the institute;
- the implementation of structural changes at iMM to successfully follow the ERA Priorities Roadmap;
- the expansion of overseas collaborations and an improved integration of iMM in the regional, national and international business community.
Why a Forum and a database?
To establish a translational biomedical research hub anchored in Lisbon that will leverage the national potential beyond borders and act as the interface of Europe with America and Africa, it’s key to create of a forum for overseas discussion in translational immunity and infection and a database gathering experts or companies in translational immunity and infection.
The database goal is to establishing international collaborations under EU, or other (bi-national) international collaborative networks that require the participation of both academic and industrial partners. Registered users will be able to enter the experts registry and contact individuals or companies, and potentially start new collaborations in translational immunity and infection in Europe, Africa and America.
For more information visit our Forum for overseas discussion in translational immunity and infection.
This will include news, seminars, job opportunities, funding opportunities, entrepreneurial opportunities, regulatory news, successful collaboration cases and other information regarding the project EXCELLtoINNOV.
Forum Link: https://www.linkedin.com/groups/12026752
"This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 667824."
Nature Immunology - "Interleukin 17 is a chief orchestrator of immunity"
Frontiers in Immunology - "Intestinal Barrier Interactions with Specialized CD8 T Cells"