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Towards outstanding research and training in tumour biology at iMM

Funding Agency European Commission
Funding Programme Horizon 2020
Call/Topic H2020-TWINN-2015 / H2020-TWINN-2015 - Twinning
Project reference 692322
Start date 2016.01.01
Duration 36 months
Total investment EUR 999 975 (EU contribution: EUR 999 975)
Project Coordinator Edgar Gomes
Project Beneficiaries Instituto de Medicina Molecular (iMM, Portugal); Institut Curie, France; Deutsches Krebsforschungszentrum (DKFZ), Germany
This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 692322.  


Cancer is a major societal health issue in Europe. In 2012, cancer accounted for around 1.3 million deaths and an estimated economic impact of around € 126 billion in the European Union (EU).

The Instituto de Medicina Molecular João Lobo Antunes (iMM) aims to fight this destructive disease by reinforcing its capacity for outstanding pre-clinical and translation research, and by creating a dynamic cluster of excellence within the Lisbon region in the field of cancer research. Towards this goal, IMM is building up a network for outstanding research and innovation with two leading research institutes, the Institut Curie (the largest European cancer research centre), and the DKFZ - Deutsches Krebsforschungszentrum (the largest cancer research institute in Germany), the ReTuBi consortium.

ReTuBi targets 4 specific scientific areas:

  1. Cancer Stem Cells;
  2. Cancer Signalling;
  3. Cancer Invasion and Metastasis;
  4. Tumour Angiogenesis.

ReTuBi is designed to stimulate the establishment of novel and long-lasting interactions between groups at iMM, Institut Curie and DKFZ. The dynamic and intensive research framework is focused on promoting the exchange of know-how in research excellence and cutting-edge technologies to tackle current and future challenges in tumour biology. Through this initiative, ReTuBi expects an increase of 30% in multiple indicators until 2020, including the number of citations per publication; h-index of iMM researchers; percentage of publications in top 10% impact journals; number of filed patents; and number of international collaborative projects. ReTuBi will also have an impact in the entire IMM community and Lisbon area, through organisation of open scientific meetings, summer schools, and workshops.
ReTuBi extensive dynamic network of interactions will provide a channel of knowledge transfer to potentiate already existent scientific and innovative capacity within iMM, promoting an overall increase in competitiveness of Portugal and EU.