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Interestingly, we intimateness observed that GSDMD Cterm is a soluble protein, while GSDMD Nterm is insoluble and aggregates, when GSDMD is cleaved in the absence of a target membrane (Fig 3 ).


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Trx1 discriminates between CD30 and other members of the TNFR supergenealogy Ectodomains of TNFR superkindlyred proteins typically are composed of as a rule to four cysteine-rich domains (CRDs), each normally harboring three disulfide bonds ( Bodmer et al, 2002 ).

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