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A Unidade de Patologia Comparada funciona como estrutura de apoio à investigação feita com recurso a modelos animais e de doença humana. Oferecemos desde o apoio técnico no planeamento experimental, ao processamento histológico de amostras biológicas, consultoria em patologia e microscopia electrónica. Estes serviços estão também disponíveis para investigadores externos.

O que são a medicina e patologia comparadas?

Medicina Comparada e Patologia Comparada são divisões da medicina experimental e patologia que visam compreender fenómenos comuns a doenças de todas as espécies, incluindo a humana. A investigação centra-se nas semelhanças e diferenças entre espécies e em como objectivo o desenvolvimento, validação e utilização de modelos animais (tanto tanto espontâneos como induzidos) no estudo da etiologia, patogénese e tratamento da doença humana e veterinária. A disciplina também inclui o estudo da biologia normal dos animais utilizados como modelos laboratoriais.

Mais Informações:

Comparative Pathology Wiki (em inglês)

Formulário Requisições

Services


RESEARCH HISTOLOGY
  • Processing, inclusion, sectioning and HE staining - paraffin; embedding and sectioning - cryostat;
  • Histochemistry/special stains.

IMMUNOHISTOCHEMISTRY
  • Protocol optimisation;
  • Testing of antibodies on project tissue.

TEM - Transmission Electron Microscopy

TEM services are provided by Instituto Gulbenkian de Ciência (IGC). Researchers interested in doing TEM, please contact Ana Biscaia Santos (anabsantos@medicina.ulisboa.pt) in order to initiate communication with IGC.


PATHOLOGIST SERVICES
  • Temporarily, Pathology services will be provided by Instituto Gulbenkian de Ciência’s Histopathology Unit. More information here.
  • All researchers interested in doing Pathology assessment, should contact our service (imm-histologyservice@medicina.ulisboa.pt) for further information.
  • For experimental design, all researchers are advised to contact Pathologist Pedro Faísca (rfaisca@igc.gulbenkian.pt) in the beginning of theirs projects.

For prices consult our price table.

How to use the service

  1. Cryostat utilisation requires booking online. Users must request booking permission online (induction/training required);
  2. Online requisition (link bellow) should be properly filled and submitted prior to sample delivery;
  3. Researchers will be notified by e-mail as soon as the work is complete, and should collect the slides at the lab; when the work is for pathology assessment the slides will be immediately re-directed to the pathologist (be sure to include all details regarding experimental setting and expected outcome of the pathology assessment in the request form or contact the pathologist).

Requisition form

Important Note:

If you have any inquiries or suggestions you can either contact us directly by e-mail (imm-histologyservice@medicina.ulisboa.pt) or contact our representatives:

Sara Silva Pereira – Postdocs representative (ssilvapereira@medicina.ulisboa.pt)

Joana Mateus – PhD Students representative (joana.mateus@medicina.ulisboa.pt)

Acknowledgments

Acknowledgments or Authorship

Manuscripts and grants presenting work supported by our lab should include the following acknowledgement:

"We would like to thank the Comparative Pathology Unit of Instituto de Medicina Molecular João Lobo Antunes for their technical support."

Authorship is not mandatory but inclusion of the Pathologist or Histotechnician may be beneficial for the purposes of manuscript preparation and peer-review.

Please, consider authorship for the Pathologist or Histotechnician when our staff is significantly involved in experimental design and sample preparation, in generating a major portion of results and analysis, and/or in manuscript preparation.

We thank you in advance for acknowledging our efforts and contributing to the future success of our laboratory!

Equipa

Histology and Comparative Pathology Area Manager:
Ana Biscaia Santos
anabsantos@medicina.ulisboa.pt

Senior Technician:
Ana Margarida Cristovão
amcristovao@medicina.ulisboa.pt