Full Name: José Miguel Rino Henriques

Publishing Name: José Rino

ResearcherID: I-2990-2013

Date of Birth: 12th September 1976

Nationality: Portuguese

E-mail address: joserino@medicina.ulisboa.pt

• STaQTool: Spot tracking and quantification tool for monitoring splicing of single pre-mRNA molecules in living cells, Rino J, de Jesus AC, Carmo-Fonseca M. Methods 2016

• Single-Molecule Live-Cell Visualization of Pre-mRNA Splicing, Martin RM, Rino J, de Jesus AC, Carmo-Fonseca M. Methods Mol Biol 2016

• Decrease of CD68 Synovial Macrophages in Celastrol Treated Arthritic Rats, Cascão R, Vidal B, Lopes IP, Paisana E, Rino J, Moita LF, Fonseca JE. PLoS One 2015

• Adenosine A2A Receptors Modulate α-Synuclein Aggregation and Toxicity, Ferreira DG, Batalha VL, Vicente Miranda H, Coelho JE, Gomes R, Gonçalves FQ, Real JI, Rino J, Albino-Teixeira A, Cunha RA, Outeiro TF, Lopes LV. Cereb Cortex 2015

• Alterations of Nuclear Architecture and Epigenetic Signatures during African Swine Fever Virus Infection, Simões M, Rino J, Pinheiro I, Martins C, Ferreira F. Viruses 2015

• Single-Molecule Imaging of RNA Splicing in Live Cells, Rino J, Martin RM, Carvalho C, de Jesus AC, Carmo-Fonseca M. Methods Enzymol 2015

• Synthesis, characterization and biological evaluation of carboranylmethylbenzo[b]acridones as novel agents for boron neutron capture therapy, da Silva AF, Seixas RS, Silva AM, Coimbra J, Fernandes AC, Santos JP, Matos A, Rino J, Santos I, Marques F. Org Biomol Chem 2014

• Phosphorylation modulates clearance of alpha-synuclein inclusions in a yeast model of Parkinson's disease, Tenreiro S, Reimão-Pinto MM, Antas P, Rino J, Wawrzycka D, Macedo D, Rosado-Ramos R, Amen T, Waiss M, Magalhães F, Gomes A, Santos CN, Kaganovich D, Outeiro TF. PLoS Genet 2014

• Enteric mucosa integrity in the presence of a preserved innate interleukin 22 compartment in HIV type 1-treated individuals, Fernandes SM, Pires AR, Ferreira C, Foxall RB, Rino J, Santos C, Correia L, Poças J, Veiga-Fernandes H, Sousa AE. J Infect Dis 2014

• Imaging dynamic interactions between spliceosomal proteins and pre-mRNA in living cells, Rino J, Martin RM, Carvalho T, Carmo-Fonseca M. Methods 2014

• Live-cell visualization of pre-mRNA splicing with single-molecule sensitivity, Martin RM, Rino J, Carvalho C, Kirchhausen T, Carmo-Fonseca M. Cell Rep 2013

• Histone methyltransferase SETD2 coordinates FACT recruitment with nucleosome dynamics during transcription, Carvalho S, Raposo AC, Martins FB, Grosso AR, Sridhara SC, Rino J, Carmo-Fonseca M, de Almeida SF. Nucleic Acids Res 2013

• Synthesis and biological studies of pyrazolyl-diamine Pt(II) complexes containing polyaromatic DNA-binding groups, Gama S, Mendes F, Esteves T, Marques F, Matos A, Rino J, Coimbra J, Ravera M, Gabano E, Santos I, Paulo A. Chembiochem 2012

• VEGFR2 translocates to the nucleus to regulate its own transcription, Domingues I, Rino J, Demmers JA, de Lanerolle P, Santos SC. PLoS One 2011

• Spliceosome assembly is coupled to RNA polymerase II dynamics at the 3' end of human genes, Martins SB, Rino J, Carvalho T, Carvalho C, Yoshida M, Klose JM, de Almeida SF, Carmo-Fonseca M. Nat Struct Mol Biol 2011

• Nuclear targeting with cell-specific multifunctional tricarbonyl M(I) (M is Re, (99m)Tc) complexes: synthesis, characterization, and cell studies, Esteves T, Marques F, Paulo A, Rino J, Nanda P, Smith CJ, Santos I. J Biol Inorg Chem 2011

• RNA seeds nuclear bodies, Carmo-Fonseca M, Rino J. Nat Cell Biol 2011

• Tricarbonyl M(I) (M = Re, (99m)Tc) complexes bearing acridine fluorophores: synthesis, characterization, DNA interaction studies and nuclear targeting, Esteves T, Xavier C, Gama S, Mendes F, Raposinho PD, Marques F, Paulo A, Pessoa JC, Rino J, Viola G, Santos I. Org Biomol Chem 2010

• Low doses of ionizing radiation promote tumor growth and metastasis by enhancing angiogenesis, Sofia Vala I, Martins LR, Imaizumi N, Nunes RJ, Rino J, Kuonen F, Carvalho LM, Rüegg C, Grillo IM, Barata JT, Mareel M, Santos SC. PLoS One 2010

• IL-7 induces rapid clathrin-mediated internalization and JAK3-dependent degradation of IL-7Ralpha in T cells, Henriques CM, Rino J, Nibbs RJ, Graham GJ, Barata JT. Blood 2010

• The spliceosome: a self-organized macromolecular machine in the nucleus?, Rino J, Carmo-Fonseca M. Trends Cell Biol 2009

• Frontiers in fluorescence microscopy, Rino J, Braga J, Henriques R, Carmo-Fonseca M. Int J Dev Biol 2009

• Conjugation of human topoisomerase 2 alpha with small ubiquitin-like modifiers 2/3 in response to topoisomerase inhibitors: cell cycle stage and chromosome domain specificity, Agostinho M, Santos V, Ferreira F, Costa R, Cardoso J, Pinheiro I, Rino J, Jaffray E, Hay RT, Ferreira J. Cancer Res 2008

• Splicing factors SF1 and U2AF associate in extraspliceosomal complexes, Rino J, Desterro JM, Pacheco TR, Gadella TW Jr, Carmo-Fonseca M. Mol Cell Biol 2008

• Inactivation of cleavage factor I components Rna14p and Rna15p induces sequestration of small nucleolar ribonucleoproteins at discrete sites in the nucleus, Carneiro T, Carvalho C, Braga J, Rino J, Milligan L, Tollervey D, Carmo-Fonseca M. Mol Biol Cell 2008

• A stochastic view of spliceosome assembly and recycling in the nucleus, Rino J, Carvalho T, Braga J, Desterro JM, Lührmann R, Carmo-Fonseca M. PLoS Comput Biol 2007

• Depletion of the yeast nuclear exosome subunit Rrp6 results in accumulation of polyadenylated RNAs in a discrete domain within the nucleolus, Carneiro T, Carvalho C, Braga J, Rino J, Milligan L, Tollervey D, Carmo-Fonseca M. Mol Cell Biol 2007

• Studies on the role of NonA in mRNA biogenesis, Kozlova N, Braga J, Lundgren J, Rino J, Young P, Carmo-Fonseca M, Visa N. Exp Cell Res 2006

• Photobleaching microscopy reveals the dynamics of mRNA-binding proteins inside live cell nuclei, Braga J, Rino J, Carmo-Fonseca M. Prog Mol Subcell Biol 2004

• Human topoisomerase IIalpha: targeting to subchromosomal sites of activity during interphase and mitosis, Agostinho M, Rino J, Braga J, Ferreira F, Steffensen S, Ferreira J. Mol Biol Cell 2004

• The intranuclear mobility of messenger RNA binding proteins is ATP dependent and temperature sensitive, Calapez A, Pereira HM, Calado A, Braga J, Rino J, Carvalho C, Tavanez JP, Wahle E, Rosa AC, Carmo-Fonseca M. J Cell Biol 2002