StemCell2MAX is a spin-off from Instituto de Medicina Molecular and markets a proprietary mix of neurotrophic factors that are able to stimulate the expansion of haematopoietic stem cells (HSCs), highly improving their utility in research and potential clinical use. The value proposition of StemCell2MAX's products relies on the ability to expand HSCs up to 20 times over the current state-of-the-art, while maintaining their unique stem cell properties, as published in Nature by our group (Fonseca-Pereira et al, Nature 2014).
The research that lead to these results was funded by the European Research Council, European Molecular Biology Organization, National blood Foundation, US and Fundação para a Ciência e Tecnologia, Portugal (circa 2.5 million euros investment), together constituting strong evidence regarding the quality of the research. This discovery won in 2014 the prestigious Pfizer Award for basic research.
HSCs give rise to cells of the blood and lymph system and can be obtained from different sources. Common sources include bone marrow, umbilical cords and peripheral blood of a patient or an adult donor. However, HSCs are scarce and expensive. There is therefore a need for techniques that are able to improve the availability and utility of HSCs in the lab, as they are extensively used in the development of urgently needed treatments for other diseases, including HIV, multiple sclerosis.
Additionally, for many blood cell malignancies such as certain types of leukaemia and multiple myeloma, HSC transplantation is an important therapeutic option. However, due to the limited number of stem cells available, only 10% of patients referred for cord blood transplantation are eligible, which highlights the crucial contribution of StemCell2MAX for healthcare improvement.
Maria Brandão de Vasconcelos (Eng., MBA) | Chief Executive Officer & Co-founder
Filipa Matos Baptista (PhD) | Chief Marketing Officer & Co-founder
Henrique Veiga-Fernandes (PhD) | Chief Scientific Officer & Co-founder
Diogo Fonseca-Pereira (PhD) | Post-Doc Researcher & Co-founder
Sílvia Arroz-Madeira (PhD Student) | Researcher & Co-founder
For more information, visit www.stemcell2max.com