Bio
Hey there! I am Nuno, the PhD student (not to be confused with Nuno, the mastermind)! I am a molecular biologist and computer scientist with a deep interest in the development and improvement of bioinformatics methods to better characterise molecular mechanisms in physiological and disease contexts. During my spare time, I quite enjoy listening to rock and orchestral music, reading about graphic design and science, watching anime and playing JRPGs.
Since I started working on my Master’s thesis, I have been
developing psichomics, an
interactive R package for transcriptomic
analyses of large publicly available datasets. My
PhD project is focused on the biogenesis and
putative functional roles of circular RNAs and
will (hopefully) offer novel insights into RNA
biology, including the discovery of new
biomarkers for cancer and
neurodegeneration.
Publications
Saraiva-Agostinho N+, Barbosa-Morais NL+. "Interactive Alternative Splicing Analysis of Human Stem Cells Using psichomics."
Methods in Molecular
Biology,2020;2117:179-205. doi: 10.1007/978-1-0716-0301-7_10. [PUBMED]
(+ corresponding author)
Saraiva-Agostinho N+, Barbosa-Morais NL+. "psichomics: graphical application for alternative splicing quantification and analysis."
Nucleic Acids Research, 2019 Jan 25;47(2):e7. doi: 10.1093/nar/gky888. [PUBMED]
(+ corresponding author)
. Press
release: "New approach on the use of big data in clinical decision support"
Gallego-Paez LM, Bordone MC, Leote AC, Saraiva-Agostinho N, Ascensao-Ferreira M, Barbosa-Morais NL. "Alternative splicing: the pledge, the turn, and the prestige - The key role of alternative splicing in human biological systems." Human Genetics, 2017 Sep;136(9):1015-1042. [PUBMED]
Deng M, Brägelmann J, Kryukov I, Saraiva-Agostinho N, Perner S. "FirebrowseR: an R client to the Broad Institute's Firehose Pipeline." Database (Oxford), 2017 Jan 6;2017. pii: baw160. doi: 10.1093/database/baw160. [PUBMED]